Table 3.
Distribution of predicted values and characteristics of CNFD, CNBD, CNFL, and CTBD parameters for ROC test by groups of subjects.
| Parameter/Threshold Value | Area under ROC Curve (%) | Sensitivity/Specificity (%) | HSV Affected Patients/Herpes Labialis and Healthy Controls (%) |
p-Value | OR of HSV Affected Patients (95% CI) |
|---|---|---|---|---|---|
| CNFD herpetic eye <3.13 |
87.5 | 78.5 91.1 |
78.5 8.9 |
<0.001 | 37.114 (17.847–77.184) |
| CNFD healthy eye <15.62 |
70.0 | 80.6 50.5 |
80.6 49.5 |
<0.001 | 4.242 (2.173–8.282) |
| CNBD herpetic eye <3.13 | 80.0 | 82.3 76.3 |
82.3z 23.7 |
<0.001 | 14.96 (7.676–29.158) |
| CNBD healthy eye <16.15 |
62.2 | 73.1 50.5 |
73.1 49.5 |
0.001 | 2.78 (1.51–5.119) |
| CNFL herpetic eye <9.92 |
80.6 | 83.5 65.3 |
83.5 34.7 |
<0.001 | 9.538 (4.903–18.557) |
| CNFL healthy eye <10.07 |
68.9 | 67.2 63.7 |
67.2 36.3 |
<0.001 | 3.587 (1.99–6.467) |
| CTBD herpetic eye <15.62 |
67.1 | 58.2 72.6 |
58.2 27.4 |
<0.001 | 3.699 (2.136–6.407) |
| CTBD healthy eye <37.5 |
61.3 | 80.6 41.6 |
80.6 58.4 |
0.001 | 2.956 (1.512–5.782) |
OR—odds ratio; CI—confidence interval.