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. 2019 May 27;55(5):214. doi: 10.3390/medicina55050214

Table 4.

Quantitative analysis of corneal sub-basal nerve changes during the first visit and follow up.

HSV Affected Eye
n = 79
Contralateral Eye
n = 79
Herpes Labialis Group
n = 101
Healthy Controls
n = 89
First Visit Follow up First Visit Follow up
CNFD n/mm2 2.5 ± 5.7 a,b1 6.5 ± 7.0 a,b6,c,e 9.9 ± 7.6 a,b1 12.6 ± 10.3 a,b6,d 19.1 ± 12.2 c,d 15.8 ± 10.8 e
CNBD n/mm2 2.7 ± 7.2 a,b1 8.1 ± 10.7 a,b6,c,e 11.7 ± 13.5 a,b1 15.2 ± 16.2 a,b6 22.0 ± 20.7 c 21.3 ± 24.2 e
CNFL mm/mm2 6.3 ± 4.3 b1 7.3 ± 4.3 b6,c,e 9.6 ± 6.3 a,b1,d,f 9.7 ± 4.2 a,b6 12.8 ± 5.2 c,d 11.9 ± 4.9 e,f
CTBD n/mm2 20.1 ± 21.9 22.2 ± 18.5 c,e 25.2 ± 20.6 a 29.7 ± 25.6 a 38.4 ± 31.2 c 38.9 ± 34 e
a,b1,b6,c,d,e,fp < 0.05

ap value between parameters of the first visit and follow up; b1p value between parameters of HSV affected and contralateral eyes during the first visit; b6p value between parameters of HSV affected and contralateral eyes during follow up by Wilcoxon test; cp value between parameters of HSV affected eye during follow up and herpes labialis group; dp value between parameters of contralateral eye during follow up and herpes labialis group; ep value between parameters of HSV affected eye during follow up and healthy controls; fp value between parameters of contralateral eye during follow up and healthy controls by the Mann-Whitney test.