Table 3.
Comparison of laboratory results between obstructive sleep apnea syndrome (OSAS) patients with (HOMA-IR ≥ 2) and without (HOMA-IR < 2) insulin resistance.
| OSAS Patients With HOMA IR < 2 n = 34 |
OSAS Patients With HOMA IR ≥ 2 n = 58 |
p | |
|---|---|---|---|
| FEV1 (% predicted) | 96.5 ± 21.3 | 90.1 ± 21 | 0.201 |
| FVC (% predicted) | 95 ± 16.4 | 85.8 ± 20.9 | 0.052 |
| FEV1/FVC (%) | 83.2 (78–88.6) | 82 (73.2–96.8) | 0.485 |
| pO2 (mmHg) | 81.4 ± 12.7 | 75.3 ± 11.1 | 0.022 |
| pCO2 (mmHg) | 40 (39–42.4) | 40.7 (38.6–44.8) | 0.809 |
| Glucose (mg/dL) | 84 ± 11 | 104 ± 17 | < 0.001 |
| HOMA–IR | 1.1 (0.5–1.6) | 5.5 (3.2–15.1) | < 0.001 |
| Cholesterol (mg/dL) | 207 ± 48 | 208 ± 39 | 0.952 |
| Triglycerides (mg/dL) | 108 (84–177) | 167 (115–227) | 0.010 |
| LDL-C (mg/dL) | 107 (80–148) | 109 (100–150) | 0.338 |
| HDL-C (mg/dL) | 48 ± 11 | 46 ± 13 | 0.405 |
| CRP (mg/dL) | 0.25 (0.09–0.63) | 0.46 (0.14–0.96) | 0.199 |
| 25(OH)D (ng/mL) | 26.7 ± 12.2 | 19.3 ± 11.5 | 0.005 |
CRP: C-reactive protein, FEV1: Forced expiratory volume in 1st sec, FVC: Forced vital capacity, HDL-C: High density lipoprotein-cholesterol, HOMA-IR: Homeostatic Model Assessment of Insulin Resistance, LDL-C: Low density lipoprotein-cholesterol, pCO2: Carbon dioxide partial pressure, pO2: Oxygen partial pressure, 25(OH)D: 25-hydroxyvitamin D.