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. 2019 May 16;8(5):694. doi: 10.3390/jcm8050694

Figure 8.

Figure 8

Selected parameters (routine, OXPHOS and electron transport system (ETS)) of mitochondrial respiration in permeabilized C2C12 myoblasts after treatment with statins at IC50 (ATR, atorvastatin; SIM, simvastatin) and geranylgeraniol (GGOH; 10 µM) or cholesterol (Chol-PEG; 1 mM). Data were expressed as the mean ± standard deviation (SD) and the raw data, n = 5. The significance of differences was estimated based on: One-way ANOVA test and Tukey’s test as post hoc; (A) p < 0.05 for ATR vs. ATR + GGOH, ATR vs. SIM, ATR + GGOH vs. ATR + Chol; p < 0.001 for CTRL vs. ATR; CTRL vs. ATR + Chol; (B) p < 0,001 for CTRL vs. ATR, p < 0,05 for CTRL vs. ATR + Chol; (C) p < 0,01 for CTRL vs. ATR, CTRL vs. ATR+Chol; more experimental details see ‘Material and Methods’.