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. 2019 May 23;11(5):916. doi: 10.3390/polym11050916

Figure 7.

Figure 7

Epithelial-to-mesenchymal transition (EMT)-related and stemness gene expression. Stemness (Sox2) and EMT-related (Snail, E-cadherin, and Vimentin) gene expression of MDA-MB-231 culture in 2D (black bars) and in 3D (grey bars) using 15% PLA ES scaffolds over three days (left) and six days (right). Experiments were performed at least three times. For an easier interpretation, the value obtained for cells cultured in 2D was adjusted to 1 and that of the 3D-cultured cells was calculated based on this. * (p < 0.05) indicates levels of statistical significance.