Table 1.

Major study characteristics from the ten RCTs included in the meta-analysis

Literature	Year	Treated Patients	Placebo	Therapy strategy	Duration of therapy	Jadad Scale
Suzuki et al9	2001	55	54	Erythromycin 200–400 mg once daily	12 months	2
Banerjee et al10	2004	31	36	Clarithromycin 500 mg once daily	3 months	3
Seemungal et al11	2008	53	56	Erythromycin 250 mg twice daily	12 months	5
He et al12	2010	18	18	Erythromycin 125 mg three times daily	6 months	4
Albert et al13	2011	558	559	Azithromycin 250 mg once daily	12 months	3
Berkhof et al14	2013	42	42	Azithromycin 250 mg three times a week	3 months	5
Uzun et al15	2014	47	45	Azithromycin 500 mg three days a week	12 months	5
Simpson et al16	2014	15	15	Azithromycin 250 mg once daily	12 months	5
Shafuddin et al17	2015	97	94	Roxithromycin 300 mg once daily	3 months	5
Ra et al18	2017	504	499	Azithromycin 250 mg once daily	12 months	4

Abbreviation: RCTs, randomized controlled trials.