Table 2.

Comparison of Perioperative Clinicopathologic Characteristics and Outcomes between ESCC and ESCC-R with Stage II/III Disease that Underwent Surgery

Characteristic N (%)	Overall (N= 216)	ESCC (N= 192)	ESCC-R (N= 24)	P
Neoadjuvant Therapy
Any	165 (76.4)	151 (78.6)	14 (58.3)	0.039
Chemo Alone	13 (6)	6 (3.1)	7 (29.2)	<.001
Chemoradiation	147 (68.1)	140 (72.9)	7 (29.2)	<.001
ASA
2	79 (36.6)	73 (38)	6 (25)	0.22
3	127 (58.8)	110 (57.3)	17 (70.8)
4	4 (1.9)	3 (1.6)	1 (4.2)
NA	6 (2.8)	6 (3.1)	0 (0)
Minimally Invasive Surgery	23 (10.6)	19 (9.9)	4 (16.7)	0.317
Procedure
Ivor-Lewis	106 (49.1)	95 (49.5)	11 (45.8)	0.157
3-Hole	71 (32.9)	63 (32.8)	8 (33.3)
Transhiatal	12 (5.6)	11 (5.7)	1 (4.2)
Pharyngo-/Laryngo-esophagectomy	4 (1.9)	3 (1.6)	1 (4.2)
Aborted	4 (1.9)	2 (1)	2 (8.3)
NA	19 (8.8)	18 (9.4)	1 (4.2)
Vascular Invasion	39 (18.1)	32 (16.7)	7 (29.2)	0.143
Neural Invasion	41 (19)	30 (15.6)	11 (45.8)	0.001
R0 Resection	178 (82.4)	160 (83.3)	18 (75)	1
pT Stage
0 (pathologic complete response)	78 (36.1)	74 (38.5)	4 (16.7)	0.024
1	24 (11.1)	23 (12)	1 (4.2)
2	25 (11.6)	24 (12.5)	1 (4.2)
3	70 (32.4)	56 (29.2)	14 (58.3)
4	7 (3.2)	6 (3.1)	1 (4.2)
NA	12 (5.6)	9 (4.7)	3 (12.5)
pN Stage
0	134 (62)	123 (64.1)	11 (45.8)	0.401
1	49 (22.7)	41 (21.4)	8 (33.3)
2	16 (7.4)	15 (7.8)	1 (4.2)
3	3 (1.4)	3 (1.6)	0 (0)
NA	14 (6.5)	10 (5.2)	4 (16.7)
Length of Stay, Days Median (IQR)	13 (6, 119)	13 (6, 119)	16 (6, 71)	0.22
30 Day Complications
Any	107 (49.5)	95 (49.5)	12 (50)	1
Serious	59 (27.3)	50 (26)	9 (37.5)	0.803
Leak	28 (13)	24 (12.5)	4 (16.7)	1
30 Day Reoperation	27 (12.5)	23 (12)	4 (16.7)	0.756
30 Day Readmission	10 (4.6)	10 (5.2)	0 (0)	0.614
30 Day Mortality	6 (2.8)	4 (2.1)	2 (8.3)	0.136
In-House Mortality	12 (5.6)	8 (4.2)	4 (16.7)	0.032