Table 4.
Study characteristics of 42 clinical trials registered on ClinicalTrials.gov based on ClinicalTrials.gov data
| Characteristics | No. (%) or median (IQR) | |
|---|---|---|
| New clinical trial N = 28 |
Complete or submit results from ongoing clinical trials N = 16 |
|
| Randomization | ||
| Yes | 26 (92.9) | 10 (62.5) |
| No | 2 (7.1) | 6 (37.5) |
| Allocation | ||
| Double blind | 22 (78.6) | 6 (37.6) |
| Open label | 6 (21.4%) | 10 (62.5) |
| Comparator | ||
| Placebo | 18 (64.3) | 6 (37.5) |
| Active | 4 (14.3) | 4 (25.0) |
| None | 6 (21.4) | 6 (37.5) |
| Endpoint | ||
| Surrogate outcome | 6 (21.4) | 10 (62.5) |
| Clinical outcome | 5 (17.9) | 3 (18.8) |
| Clinical scale | 17 (60.7) | 0 (0.0) |
| Safety | 0 (0.0) | 3 (18.8) |
| Estimated sample size | 400 (254 to 529) | 237 (373 to 744) |
| Duration (months) | 1.6 (0.9 to 12.0) | 5.6 (5.2 to 12.6) |