Skip to main content
. Author manuscript; available in PMC: 2019 Jun 17.
Published in final edited form as: Glia. 2015 Apr 2;63(9):1606–1620. doi: 10.1002/glia.22831

Figure 2. Abundant microglia-neuron contacts but no neuronal loss in Mfp2−/− mice.

Figure 2.

(A-D) Activated microglia (Iba1+, green) enwrap cell bodies (DAPI, blue) in the CA3 region of the hippocampus in Mfp2−/− mice (C,D) but not in control (A,B). B and D are magnifications of the highlighted area in A and C, respectively. Nuclei are stained blue with DAPI. (E) F4/80+ cells contact NeuN neurons in the brainstem of Mfp2−/− mice. (F) Magnification of E. (G – I) H&E staining and quantification in the CA3 region of hippocampus reveals preservation of neurons in Mfp2−/− mice.