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. Author manuscript; available in PMC: 2019 Nov 2.
Published in final edited form as: J Proteome Res. 2018 Oct 10;17(11):3657–3670. doi: 10.1021/acs.jproteome.8b00270

Figure 5. Volcano plots depicting the impact of sex (A & B) and age (C & D) on circulating lipids (A & C) and their fatty acyl side chains (B & D) from 100 healthy individuals using independent testing (strategy 1).

Figure 5.

All panels depict the 799 features obtained following MS data processing from which 295 lipids were annotated using manual peak alignment with previously acquired dataset for which we had characterized the lipidome using MS/MS, including their fatty acyl side chains, as shown by the different colours. The dotted line indicates the P-value <0.05 threshold, which corresponds to FDR values of 8.5% (impact of sex) and 17% (impact of age, expressed on a one-year difference).