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. 2019 Jun 10;14:4319–4331. doi: 10.2147/IJN.S203077

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© 2019 Wang et al.

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In vivo magnetic resonance imaging (MRI) scans and tumoral heat shock protein HSP70 expression. (A) Tumor-bearing BALB/c mice were intratumorally injected with saline or NaYF₄:Yb,Er@PE₃@Fe₃O₄ nanoprobes, followed by either near-infrared irradiation (NIR) irradiation or not. Five days later, both T1- and T2-weighted MRI scans were captured from each treatment group. (B) Immunohistochemical analysis of tumoral HSP70 expression in control mice and those receiving photothermal therapy. This experiment was repeated three times.