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. 2019 Jun 14;10:2654. doi: 10.1038/s41467-019-10695-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Summary of intersegmental feedback network in motor circuits. a Model of the roles of intersegmental feedback neurons Ifb-Fwd (left) and Ifb-Bwd (right) in transforming the progression of a wave front to the intersegmental delay in forward (left) and backward (right) propagations, respectively. b Schematic of connectivity from intersegmental feedback neurons (Ifb-Fwd and Ifb-Bwd) through the shared module (A02e and A03g, as examples) to MN synergy (longitudinal MNs and transverse MNs) in the nerve cord. Ifb neurons and the shared neurons form synaptic contacts at a centrolateral region of the neuropil (arrowhead). c Schematic of functional domains within the neuropil. Intersegmental feedback signals are conveyed at the centrolateral regions (arrowheads)