Table-II.
The relationship between expressions of Topo Iiα and Ki67 and clinicopathological parameters.
| Factor | n | Topo IIα | Ki67 | |||||
|---|---|---|---|---|---|---|---|---|
| Number of positive cases | X2 | P value | Number of positive cases | X2 | P value | |||
| Age (year) | < 50 | 36 | 20 | 0.273 | >0.05 | 22 | 1.024 | >0.05 |
| ≥50 | 30 | 19 | 24 | |||||
| Menstrual status | Non-menopause | 43 | 22 | 0.317 | >0.05 | 40 | 1.648 | >0.05 |
| Menopausal | 23 | 11 | 20 | |||||
| Diameter of lesion (cm) | <2 | 35 | 18 | 8.146 | <0.05 | 19 | 7.969 | <0.05 |
| ≥2 | 31 | 28 | 27 | |||||
| Lymphatic metastasis | With | 30 | 13 | 9.723 | <0.05 | 16 | 11.174 | <0.05 |
| Without | 36 | 28 | 32 | |||||
| Pathological pattern | Invasive ductal carcinoma | 33 | 21 | 1.318 | >0.05 | 24 | 1.324 | >0.05 |
| Intraductal carcinoma | 6 | 4 | 4 | |||||
| Invasive lobular carcinoma | 20 | 10 | 12 | |||||
| Mucinous adenocarcinoma | 7 | 4 | 5 | |||||
| Clinical stage | Stage I and II | 38 | 19 | 4.576 | <0.05 | 14 | 2.178 | >0.05 |
| Stage III and IV | 28 | 21 | 22 | |||||