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Safety data on percutaneous portal vein infusion of spheroid hepatocytes. (A) Average portal pressures during injection in single-cell and spheroid animals. (B) Ultrasound images showing the presence of thrombotic events in two spheroid hepatocyte transplanted pigs (white ovals). Pig 888, near-occlusive thrombus noted in the right anterior portal vein shortly after the start of the infusion. Pig 897, occlusive thrombus noted in the right main portal vein at the end of the infusion.
