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Effect of intraperitoneal injections of subanesthetic doses of ketamine on the extracellular levels of glutamate in the prefrontal cortex. All doses tested increased these levels significantly compared with the saline injected groups.Asterisks (*) denote significant differences from saline-treated groups as determined by Kruskal–Wallis ANOVA (n = 6 for 30 mg/kg; n = 7 for 20 mg/kg; n = 7 for 10 mg/kg groups).
