Fig. 5.

These slices through the ventral striatum show a region of significant increase in CMRglc in the left nucleus accumbens of both the healthy volunteers and the alcoholics. Among the healthy volunteers glucose uptake in this region increased by 31.2 ± 23.8%; among the alcoholics the increase was 13.7 ± 19.3%. Also visible on these slices is a region of significant activation in the left middle frontal gyrus of the healthy volunteers (increase in CMRglc = 25.6 ± 19.2%). [No corresponding region of activation is detectable in the alcoholics (increase in CMRglc = 4.4 ± 8.9%).]