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. 1997 Apr 15;17(8):2766–2774. doi: 10.1523/JNEUROSCI.17-08-02766.1997

Fig. 3.

Fig. 3.

After 7–9 d in culture, decay kinetics of NMDA EPSCs depend on the type of innervation. A, B, Averages of 10 NMDA EPSCs evoked by extracellular stimulation in target neurons innervated by dg (A) and CA (B) explants. Stimulus artifacts are truncated. Holding potential: −60 mV. Note the innervation-dependent differences in decay kinetics.C–E, NMDA receptor-mediated components of mEPSCs.C, D, Individual mEPSCs recorded in a dg-innervated neuron (C) and in a CA-innervated neuron (D). Holding potential: −60 mV. NMDA receptor-mediated components after the AMPA/kainate receptor-mediated component are indicated by arrows. E, NMDA receptor-mediated components of average mEPSCs recorded in a dg-innervated neuron (dg) and in a CA-innervated neuron (CA). The AMPA/kainate receptor-mediated component is truncated. d-AP-5 (50 μm) selectively blocked the NMDA receptor-mediated components (AP-5).