Table 2.
Brain area | PPE (fg/μg) | PPD (fg/μg) | ||
---|---|---|---|---|
Saline | Cocaine | Saline | Cocaine | |
Ala | 155.42 ± 24.89 | 385.86 ± 28.142-160 | 0.0 ± 0.0 | 0.0 ± 0.0 |
Alb | 352.0 ± 41.35 | 538.1 ± 33.53* | 238.7 ± 21.2 | 352.4 ± 23.53* |
A2 | 480.87 ± 43.75 | 593.6 ± 34.75 | 62.9 ± 9.6 | 76.6 ± 4.76 |
A3 | 129.2 ± 13.85 | 163.53 ± 15.92 | 17.1 ± 3.66 | 24.1 ± 4.54 |
A4 | 648.2 ± 21.22 | 578.01 ± 45.39 | 213.3 ± 14.4 | 255.0 ± 12.46 |
A5 | 603.03 ± 16.17 | 502.77 ± 14.96* | 181.9 ± 9.8 | 121.0 ± 19.14* |
The quantities of PPE and PPD mRNA were determined in total RNA extracts from dissected brain areas A1–A5 in saline- and cocaine-treated day 70 fetal monkeys. A1–A5, Areas through the brain from rostral A1 to caudal A5. The numbers are expressed as mean ± SEM.
p < 0.05,
F2-160: p < 0.005 versus saline controls.