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. 1997 Feb 1;17(3):1064–1074. doi: 10.1523/JNEUROSCI.17-03-01064.1997

Fig. 1.

Fig. 1.

The NFHLacZ inclusions contain all three endogenous NF subunits and the NFHLacZ fusion protein. Ais a frozen section of the neocortex of a 1-week-old transgenic mouse stained with rabbit anti-NFL polyclonal antiserum (NFL). The NF-rich inclusions first appear in the perikarya of large pyramidal neurons of neocortex. B is a frozen section of the neocortex of a 6-month-old transgenic mouse stained with X-gal (X-Gal). C–F show paraffin sections of the neocortex of a 6-month-old transgenic mouse stained with RMO32 (an mAb specific for NFM), RMO24, and RMdO9 (mAbs specific for NFH) and rabbit anti-NFL antiserum. The sections inA and C–F were counterstained with hematoxylin. A–F are at the same magnification; scale bar: F, 50 μm.