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Summary of the NFHLacZ transgenic mice
| Line | Age (number pairs) | Phenotype | Loss of Purkinje cells |
|---|---|---|---|
| 44A | 1 week (2) | − | ND |
| 6 weeks (2) | − | ND | |
| 2 months (4) | + | ND | |
| 4 months (4) | + | ND | |
| 6 months (10) | + | − | |
| 12 months (3) | + | + | |
| 18 monrhs (3) | ++ | ++ | |
| 44B | 1 week (2) | − | ND |
| 6 weeks (2) | − | ND | |
| 2 months (2) | − | ND | |
| 4 months (2) | ± | ND | |
| 6 months (3) | + | ND | |
| 12 months (2) | + | ND | |
| 18 months (2) | ++ | ++ | |
Phenotype +, tremor and muscular wasting; Phenotype ++, tremor, muscular wasting, and ataxia; ND, not determined.
