Fig. 5.

Action-potential firing patterns are not changed by l-CCG (A, C) andl-AP4 (B, D) in control (A, B) and kindled neurons (C, D). Current-clamp recordings from four different BLA neurons at membrane potential −60 mV. Action potentials were generated by a transient (500 msec) depolarizing current pulse of 400 pA in the predrug period (left traces in A–D) and after 13 min in the indicated drug (middle traces in A–D).Graphs on the right inA–D show action-potential frequency calculated from the current-clamp recordings as a function of depolarizing currents injected at increasing intensities (100 pA steps) in the absence and presence of l-CCG (1.0 μm inA, C) and l-AP4 (10 μm in B; 1.0 μm inD). Data from different neurons are averaged:A, n = 3; B,n = 4; C, n = 3;D, n = 3. Symbols and error bars represent mean ± SEM. The paired t test did not indicate significant effects of either agonist (p > 0.1).