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GKAP colocalizes at excitatory synapses with GluR1. In hippocampal neurons at 3 weeks in culture, GKAP (A) is distributed in puncta that colocalize with clusters of GluR1 (B) at dendritic spines in pyramidal cells. Punctate GKAP immunoreactivity (C) does not colocalize with clusters of the GABA-R β2 and β3 subunits (D), markers of GABAergic inhibitory synapses. Scale bar, 10 μm; inset, 5 μm.
