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Ratio between ChAT activity in the cerebral cortex and number of cholinergic neurons in the basal nucleus of Meynert in patients with AD carrying different apoE genotypes. Values of both ChAT activity and neuronal number (determined on every 20th section processed for anti-ChAT immunocytochemistry) are expressed as percentages of control values. Student’s t tests were used to compare mean values of individual groups; allp < 0.001. For group size, see Table 1.
