Table 3.
Statistical summary for the analysis of frequency distribution of dendritic segments in AD compared with controls
| Effect | ApoE 3/3 | ApoE 3/4 | ApoE 4/4 | ||||
|---|---|---|---|---|---|---|---|
| df | F | df | F | df | F | ||
| Basal nucleus of Meynert | |||||||
| Control | AD | 1, 52 | 72.123-165 | 1, 37 | 143.343-165 | 1, 29 | 226.823-165 |
| AD × Lin segm.or. | 1, 52 | 32.343-165 | 1, 37 | 63.703-165 | 1, 29 | 108.193-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 8.293-160 | 1, 28 | 9.163-160 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 21.223-165 | ||||
| Locus coeruleus | |||||||
| Control | AD | 1, 52 | 43.783-165 | 1, 37 | 82.103-165 | 1, 29 | 136.163-165 |
| AD × Lin segm.or. | 1, 52 | 33.103-165 | 1, 37 | 71.903-165 | 1, 29 | 112.343-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 7.563-160 | 1, 28 | 8.723-160 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 18.323-165 | ||||
| Raphe magnus nucleus | |||||||
| Control | AD | 1, 52 | 45.283-165 | 1, 37 | 93.103-165 | 1, 29 | 129.453-165 |
| AD × Lin segm.or. | 1, 52 | 29.343-165 | 1, 37 | 58.223-165 | 1, 29 | 89.453-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 5.163-150 | 1, 28 | 4.823-150 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 8.293-160 | ||||
| Medial amygdaloid nucleus | |||||||
| Control | AD | 1, 52 | 41.183-165 | 1, 37 | 83.193-165 | 1, 29 | 124.123-165 |
| AD × Lin segm.or. | 1, 52 | 23.183-165 | 1, 37 | 48.223-165 | 1, 29 | 75.603-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 4.563-150 | 1, 28 | 5.283-150 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 7.783-160 | ||||
| Pedunculopontine tegmental nucleus | |||||||
| Control | AD | 1, 52 | 28.923-165 | 1, 37 | 62.103-165 | 1, 29 | 89.523-165 |
| AD × Lin segm.or. | 1, 52 | 22.123-165 | 1, 37 | 43.293-165 | 1, 29 | 63.173-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 5.103-150 | 1, 28 | 6.233-150 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 7.563-160 | ||||
| Substantia nigra | |||||||
| Control | AD | 1, 52 | 21.123-165 | 1, 37 | 31.193-165 | 1, 29 | 67.323-165 |
| AD × Lin segm.or. | 1, 52 | 14.203-165 | 1, 37 | 19.123-165 | 1, 29 | 38.173-165 | |
| AD: ApoE 3/4 | AD × Lin segm.or. | 1, 51 | 4.783-150 | 1, 28 | 4.313-150 | ||
| AD: ApoE 4/4 | AD × Lin segm.or. | 1, 43 | 7.303-160 | ||||
Data are F values for the comparison of subgroups of patients with AD with the control group and for comparison between AD subgroups obtained by one-way ANOVA.
F3-150: p < 0.05;
F3-160: p < 0.01;
F3-165: p < 0.001; for group size, see Table 1. Lin segm.or., Linear trend of segment order.