PGE2or E2
|
Prostaglandin E2
|
Hyperalgesic inflammatory mediator |
DAMGO or D |
[d-Ala2,N-Me-Phe4,gly5-ol] enkephalin |
μ-opioid receptor agonist |
N |
Naloxone |
Opioid receptor antagonist |
Cl |
Clonidine |
α2-adrenergic agonist |
Yo |
Yohimbine |
α2-adrenergic antagonist |
CPA |
N6-cyclopentyl-adenosine |
A1-adenosine receptor agonist |
PACPX |
1,3-dipropyl-8-(2-amino-4-chlorophenyl)-xanthine |
A1-adenosine receptor antagonist |
μ-antisense |
μ-opioid receptor oligodeoxynucleotide (ODN) |
Downregulation of μ-opioid receptors |
μ-sense |
|
No effect |
α2-antisense |
α2C-adrenergic receptor oligodeoxynucleotide (ODN) |
Downregulation of α2C-adrenergic receptors |
α2-sense |
|
No effect |