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. 1997 Jun 15;17(12):4527–4535. doi: 10.1523/JNEUROSCI.17-12-04527.1997

Fig. 3.

Fig. 3.

The effects of activity blockade and neurotrophins on the percentage of GABA-positive neurons in cortical cultures.A, Cultures were treated with 0.1 μm TTX, either alone (TTX) or in the presence of 25 ng/ml BDNF (TTX + BDNF), 50 ng/ml NGF (TTX + NGF), or 25 ng/ml NT3 (TTX + NT3) for 2 d; *significantly different from control, p< 0.01. B, The effects of different doses of BDNF on the ability of TTX to reduce the percentage of GABA-positive neurons were determined. TTX (0.1 μm) was applied in the presence of the indicated concentration of BDNF for 2 d and the percentage of GABA-positive neurons determined. For each condition inA and B, the ratio of GABA-positive to GABA-negative neurons was determined, and these values are expressed as a percent of the values obtained for control cultures (control = 100%, dashed line).