Fig. 8.
Time course study of fluo-3 fluorescence increase induced by Aβ(25–35) and prevention by melatonin. Cells were exposed to 50 μm scrambled peptide (control), 50 μmAβ(25–35), or 50 μm Aβ(25–35) plus 5 μm melatonin. Aβ alone was significantly different from control and Aβ plus melatonin after 6 hr at all time points (p < 0.002). There were no significant differences between control and Aβ plus melatonin at any time point.
