Fig. 6.

Histograms of the percentage of cells displaying GAP-43 (a) or Tα1-tubulin (c) expression in multiples of their contralateral expression level, obtained from representative animals infused with vehicle, BDNF, or NT-4/5 (marked by arrowsin b and d). The labels ofx-axis (multiples of contralateral) indicate an upper limit value of the bin category. Note the apparent shift to the right (increased expression) for both genes in the numbers of RSNs treated with BDNF or NT-4/5 compared with those treated with vehicle. Each symbol in b and d represents the mean (±SEM) of ISH signals/cell normalized to that of contralateral RSNs, i.e., expressed as multiples of contralateral derived from an individual animal. Dashed lines indicate the expression level of contralateral (=1). Note the increased expression of GAP-43 (b) as well as Tα1-tubulin (d) in the animal groups treated with BDNF or NT-4/5 compared with the vehicle or no-pump control groups.