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. 1997 Oct 1;17(19):7503–7522. doi: 10.1523/JNEUROSCI.17-19-07503.1997

Fig. 12.

Fig. 12.

Electron micrographs showing immunoreactivity for mGluR7a (A, B) and mGluR7b (C–E) in CA1 stratum radiatum (A), hilus (B), and CA3 stratum lucidum (C–E). Peroxidase reaction product for mGluR7a is accumulated along presynaptic membrane specialization of asymmetrical synapses on spines (s) of CA1 pyramidal cells (A) and symmetrical synapses on a soma (So) in the hilus (B). Immunogold particles for mGluR7b are concentrated in presynaptic membrane specialization of asymmetrical synapses on dendrites and necks of long spines (C). Symmetrical synapses on a dendrite (Den) are also labeled for mGluR7b (D). Note that the accumulation of the peroxidase reaction product is restricted to active zones of presynaptic membrane (D). E, A giant mossy fiber terminal (MT) makes a labeled synapse on a dendritic profile (asterisk) of a presumed interneuron and also makes unlabeled synapses on spines (s) of CA3 pyramidal cells. T, Axon terminal. Scale bars: 0.5 μm for A, B; 0.26 μm for C, D; 0.4 μm for E.

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