Effect of intracerebroventricular administration of zDEVD-fmk on neurological recovery after lateral fluid percussion-induced TBI. The histogram represents median scores at indicated times after trauma. Each filled circlerepresents an individual animal’s cumulative neuroscore, reflecting performance on a battery of motor tests. Open bars, Vehicle-treated injury, n = 13; filled bars, zDEVD-fmk-treated injury, n = 16. **p < 0.01 versus vehicle-treated injury, using the Mann–Whitney U test after Kruskal–Wallis nonparametric ANOVA.