Table 1.

Summary of half-life and percent of receptor on surface experiments

Experiment	Day 4	Day 11	n
GluR1 surface half-life	10.4  ± 2.2 hr	30.5  ± 12.7 hr	3
GluR1 total half-life	12  ± 1.4 hr	31  ± 4.2 hr	2
NGT half-life	10.3  ± 0.7 hr	13.2  ± 2.4 hr	3
% GluR1 on surface	32.5  ± 4.5%	68.6  ± 12.9%	5

The means ± sd for the half-lives of surface GluR1 and total GluR1 on days 4 and 11 are shown. A paired ttest demonstrated a significant increase in the half-life of surface GluR1 from day 4 to day 11 (p < 0.05). The half-life of the neuronal glutamate transporter (NGT) did not change significantly between day 4 and day 11. Also shown are values for the percent of GluR1 on the surface of spinal cord neurons. There is a significant increase in the percent of GluR1 on the surface from day 4 to day 11 (p < 0.05).