Table 2.
Thermal responsiveness of nociceptors
| AM | ||
|---|---|---|
| p75+/+ | p75−/− | |
| % Units responding to heat | 26 (5/19) | 0 (0/17)* |
| Threshold for heat response (°C) | 42.4 ± 2.4 | — |
| % Units responding to cold | 10 (1/10) | 33 (1/3) |
| C fiber | ||
|---|---|---|
| p75+/+ | p75−/− | |
| % Units responding to heat | 41 (7/17) | 64 (14/22) |
| Threshold for heat response (°C) | 38.8 ± 1.8 | 38.4 ± 1.0 |
| % Units responding to cold | 30 (3/10) | 36 (4/11) |
*
Percent of fibers in p75−/− animals significantly different from that in p75+/+ animals (p < 0.05, χ2 test). Threshold values are given as mean ± SEM.