Fig. 12.

Schematic diagram of neural circuits that may influence PKC expression during vestibular compensation. Two potential substrates for the parasagittal distribution of increased PKC expression in the flocculonodular lobe are (1) an anterograde influence of climbing fiber projections from the dorsal cap and ventrolateral outgrowth and (2) a retrograde influence via zonal projections of Purkinje cells to the vestibular nuclei. A contribution of mossy fiber–granule cell-parallel fiber and monoaminergic projections, however, cannot be excluded.