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. 1997 Jun 1;17(11):4441–4447. doi: 10.1523/JNEUROSCI.17-11-04441.1997

Fig. 1.

Fig. 1.

Locomotor and stereotypy responses of dialyzed animals during administration of an 8 mg/kg AMPH run. Groups of animals were pretreated with the escalating dose regimen (RUN 1), escalating dose and eight AMPH runs (RUN 9), or an equivalent number of saline injections (ACUTE), as described in Materials and Methods, and were exposed to saline or 8 mg/kg AMPH at 2 hr intervals (arrows) during dialysis. Stereotypy is presented as percentage of time engaged in oral behaviors. Histograms represent the cumulated response over the indicated interval (390–570 min interval ANOVA:Crossovers, F = 5.18,p < 0.05; % Oral,F = 4.00, p < 0.05). *p < 0.05, ** p < 0.01 (t > 2.57) compared with Run 1; +p < 0.05 (t > 2.80) compared with ACUTE.