Fig. 8.

Effects of intraperitoneal administration of LPS (100 μg/kg body weight) on behavioral activity (arbitrary units) in long-term intra-cerebroventricularly vehicle-infused rats (•) and intracerebroventricularly CRH-infused rats (○) (direct comparison of behavioral activity data of Fig. 6B,D). LPS was injected at 11:30 A.M. as indicated by the arrow. For additional details see legends to Figures 4 and 6. Values represent mean ± SEM (n = 6–7). *, Significantly different from intracerebroventricularly vehicle-/intraperitoneally LPS-treated rats (Student’s t test). For additional statistical analyses, see Results.