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. 1997 Jun 1;17(11):4006–4021. doi: 10.1523/JNEUROSCI.17-11-04006.1997

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Copyright © 1997 Society for Neuroscience

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Fig. 4. — A, Electron micrograph of the basal portion of a CA1 pyramidal cell soma from a ZPAD-treated slice. Although numerous lysosomes (arrows) encircle the nucleus (N) and are found within the proximal span of a basal dendrite (d), none are observed in the axon hillock (h) and initial segment (is) within this section. Vacuole-containing lysosomes (open arrows) are also evident within the perikaryal cytoplasm. Magnification, 8300×. B, Enlargement of the axon initial segment (is). Note the dense axolemmal undercoating, microtubule bundling, cisternal organelle (arrow), mitochondria (arrowheads), and paucity of lysosomes. Magnification, 15,000×.