Fig. 3.
Deactivation time constants forIK. Cells were voltage-clamped at −35 mV. Outward currents were activated by a prepulse to 0 mV. The prepulse was followed immediately by a postpulse from −60 mV to −25 mV, in steps of 5 mV. A, Currents used to measure deactivation time constants after a brief (100 msec) activation prepulse.B, Currents used to measure deactivation time constants after a long (4 sec) activation prepulse. C, Plot of average deactivation time constants against membrane potential after a short (solid circles) or a long (open circles) prepulse (mean ± SEM; n = 6). Asterisks indicate values that are significantly different (t test; p < 0.01).