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A, Effect of MCA occlusion on CBF in iNOS knockouts and wild-type controls (C57/B6). The reduction in CBF produced by MCA occlusion is similar in the two groups both in the center of the ischemic territory (Core) and at the periphery (Penumbra). B, Arterial pressure of the mice before and after MCA occlusion. Arterial pressure did not differ between controls and iNOS knockouts (p > 0.05).
