Relative changes in bcl-2mRNA in dentate gyrus, CA3 hippocampus, CA1 hippocampus, and cortex in rats at 6, 24, and 72 hr after TBI versus naive controls (n = 4/group). Data are presented as mean ± SEM and represent fold changes in sections from rats after TBI versus naive controls in the ipsilateral (closed circles) and contralateral (open circles) hemispheres. There was a significant difference in bcl-2 mRNA levels in CA1 hippocampus at 24 hr versus control (p < 0.05; Kruskal–Wallis and Dunn’s test). There was also a difference inbcl-2 mRNA levels in the dentate gyrus (p < 0.05; Kruskal–Wallis test), but the time when this difference occurred could not be determined by multiple comparisons.