Intrathecal NGF treatment. BDNF immunoreactivity is present in numerous trkA cells but in few trkB or trkC cells.a–f show preparations double-labeled for BDNF immunoreactivity (a, c, e) and either trkA (b), trkB (d), or trkC (f) in situhybridization. The asterisks indicate the location of trk-expressing cells, revealed by the in situhybridization autoradiograms. Many BDNF-immunoreactive cells show trkA labeling (a, b), but the trkB- and trkC-expressing cells are distinct from the BDNF-immunoreactive ones. Scale bars, 50 μm.