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. 1997 Nov 1;17(21):8363–8375. doi: 10.1523/JNEUROSCI.17-21-08363.1997

Table 1.

Immunoreactivities of glutamate transporter subtypes in fetal and postnatal rat CNS

GLAST GLT-1 EAAC1 EAAT4
E15 E18 P1 P10 P24 Ad E15 E18 P1 P10 P24 Ad E15 E18 P1 P10 P24 Ad E15 E18 P1 P10 P24 Ad
Neocortex
 Marginal zone ± ± ± ± ++ ++
  Layer 1 ± ± + + ± ++ ++ ++ ++ ++ + + ± ± + ±
 Cortical plate ± ++
  Layer II ± ± + + + ++ ++ + + + + ± ± ± ±
  Layer III ± ± + + + ++ ++ ++ + + + ± ± + ±
  Layer IV ± ± + + + ++ ++ + + + + ± ± ± ±
  Layer V ± ± + + + ++ ++ ++ + + + ± ± + ±
  Layer VI ± ± + + + ++ ++ ++ ++ + + ± ± ± ±
Intermediate zone ± ± ±
 Cerebral white matter ± ± ± + ± ± + + ± + ± ±
Ventricular and subventricular  zones ± ± + ± ± ± ± ±
Hippocampus ± ± + ± ++
 Stratum moleculare-lacunosum ± ± + + + + ++ ++ ++ + + + ± + ±
 Stratum radiatum ± ± + + + + ++ ++ + + + + ± + ±
 Stratum pyramidale ± ± ± ± + + + ++ + + ± ± ± ±
 Stratum oriens ± ± + + + + ++ ++ ++ + + + ± + ±
 Granular layer ± ± ± ± + + + ++ + + ± ± ±
Olfactory bulb ± ± ± ± + + ± ± + + ++ ++ / ± + + + + ± ± ±
Ganglionic eminence ± ± + ± ± ± ±
Striatum ± ± ± ± + + ± + ++ ++ ± ++ ++ ++ + + ± + ±
Globus pallidus ± ± ± ± + + + ± + ++ ++ ± ++ + + + + ± ±
Septum ± ± ± ± + + ± ± ± + ++ ++ ± + + + + + + ±
Amygdala ± ± ± ± + + + ± + ++ ++ ± ++ + + + + ± ±
Thalamus ± ± ± ± ± + + ++ ++ ± ± + + + + ± ± ±
Hypothalamus ± ± ± ± + + ± + + + ++ ++ ± ± + + + +
Tectum ± ± ± ± ± + ± + ± + ++ ++ + + ++ + +
Medulla oblongata ± ± ± ± ± ± ± + + + + + + + + ++ ± ±
Cerebellar primordium ± ± +
 Cerebellar cortex
  External granular layer
  Molecular layer + ++ ++ ± ++ ++ + + + + ++ ++
  Purkinje cell layer + ++ + + + + + ++ ++ ++ ++ + + + +
  Internal granular layer ± ± ± ± ± + + + + +
 Deep cerebellar nucleus ± ± ± + + + + + ++ + + ± ±
Spinal cord
 Posterior horn ± ± + + + + ± + + + ++ ++ + ++ ++ ++ ++ ++ ± ±
 Ventral horn ± ± + + ± ± ± + + + + + + ++ ++ ++ ++ ++ ±
 White matter ± ± ± ± ++ ++ + + + + ± ± + + +

Ad, Adult. Symbols designate no detectable (−), faint (±), moderate (+), and high (++) levels of immunoreactivity and not examined (/).