Fig. 11.

Summary of developmental changes in the laminar pattern of NMDAR1 immunoreactivity in cat neocortex. Ages at the top correspond to those examined in this study. Each cortical layer is represented by its most prominent cell type (large or small pyramidal or stellate cells). Black cells indicate high levels of NMDAR1 immunostaining; gray cells are stained less intensely. The bar at the bottom of figure is a timeline of the major anatomical events in cat visual cortex development. Note gradual decline in immunostaining of deep cortical layers (5 and 6) with age, transient elevation of staining in layer 4 between P34 and P53, and maintenance of high levels of immunostaining in layers 2/3 into adulthood.