Table 1. Genetic architecture scenarios.

Scenario	MAF	Odds ratio
(A) Common low	0.073–0.499	1.05–1.15
(B) Modest low	0.0365–0.2495	1.05–1.15
(C) Rare low	0.0146–0.0998	1.05–1.15
(D) Rare medium	0.0146–0.0998	1.28–2.01
(E) Rare high	0.0073–0.0499	1.63–4.05

Note:

Allele distributions as modeled by Pawitan, Seng & Magnusson (2009).