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. 2019 Jun 17;2019(6):CD002253. doi: 10.1002/14651858.CD002253.pub4

Comparison 9. Vaginal misoprostol versus sublingual misoprostol.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Complete miscarriage < 13 weeks 5 513 Risk Ratio (M‐H, Random, 95% CI) 0.84 [0.61, 1.16]
2 Complete miscarriage 13‐23 weeks 1 9 Risk Ratio (M‐H, Fixed, 95% CI) 0.5 [0.13, 2.00]
3 Blood loss: excessive (> menstruation) 2 340 Risk Ratio (M‐H, Random, 95% CI) 0.54 [0.15, 1.89]
4 Pain 3 392 Risk Ratio (M‐H, Fixed, 95% CI) 0.58 [0.46, 0.74]
5 Nausea 4 302 Risk Ratio (M‐H, Random, 95% CI) 0.42 [0.12, 1.44]
6 Vomiting 2 300 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.46, 1.26]
7 Diarrhoea 4 472 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.54, 0.92]