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. 2019 Jun 17;2019(6):CD002253. doi: 10.1002/14651858.CD002253.pub4

Comparison 18. Buccal misoprostol lower versus higher‐dose regimen.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Complete miscarriage 13‐23 weeks 1 270 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.58, 0.86]
1.1 Complete miscarriage < 1 day 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.64 [0.46, 0.89]
1.2 Complete miscarriage < 2 days 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.60, 0.96]
2 Nausea 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.28, 1.34]
2.1 Gestation 14‐24 weeks 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.28, 1.34]
3 Vomiting 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.30 [0.12, 0.76]
3.1 Gestation 14‐24 weeks 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.30 [0.12, 0.76]
4 Diarrhoea 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.40 [0.19, 0.82]
4.1 Gestation 14‐24 weeks 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.40 [0.19, 0.82]
5 Pain 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.96 [0.87, 1.06]
5.1 Gestation 14‐24 weeks 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.96 [0.87, 1.06]
6 Woman's satisfaction with treatment (satisfied or very satisfied) 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.78, 1.17]
6.1 Gestation 14‐24 weeks 1 135 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.78, 1.17]