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. 2019 Jun 17;2019(6):CD002253. doi: 10.1002/14651858.CD002253.pub4

Comparison 22. Misoprostol intravaginal extraamniotic versus vaginal misoprostol.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Complete miscarriage 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 1.10 [1.00, 1.22]
2 Nausea 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 1.57 [1.33, 1.85]
3 Vomiting 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.25 [0.05, 1.14]
4 Diarrhoea 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.2 [0.01, 4.11]
5 Pain (use of analgesics) 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.30 [0.16, 0.58]
6 Time to expulsion 1 180 Mean Difference (IV, Fixed, 95% CI) ‐4.81 [‐5.66, ‐3.96]