Jain 1996*.

Methods	"Random number table". From the Department of Obstetrics and Gynecology, University of Southern California School of Medicine; no information on study duration.
Participants	70 women in Los Angeles, USA, with either fetal death (n = 40) or medical or genetic indications for termination of pregnancy (n = 30) at 12‐22 weeks. Only data from pregnancies complicated by fetal death included here.
Interventions	Vaginal misoprostol 200 mcg 12‐hourly plus laminaria tents (n = 20) vs vaginal misoprostol 200 mcg 12‐hourly alone (n = 18).
Outcomes	Miscarriage.
Funding	No information on funding.
Declarations of interest	No information on conflicts of interest.
Notes	Adverse effects are described for the groups as wholes, so are not included here. 2 women excluded from analyses ‐ 1 protocol violation; 1 was found to have interstitial ectopic pregnancy.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Comment: use of a random number table.
Allocation concealment (selection bias)	Unclear risk	Comment: no information on allocation concealment.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Comment: outcome was described for all 38 patients. 2 patients were excluded before analyses (1 protocol violation and 1 found to have interstitial ectopic pregnancy).
Selective reporting (reporting bias)	Low risk	Comment: no signs of selective reporting.
Other bias	Low risk	No other source of bias could be detected
Blinding of participants and personnel (performance bias) All outcomes	High risk	Comment: no information on blinding of patients and personnel. Due to the nature of the intervention (misoprostol with or without laminaria tents) it is unlikely that there was blinding.
Blinding of outcome assessment (detection bias) All outcomes	High risk	Comment: there is no information on blinding of outcome assessment. Considering the type of treatment (laminaria tents or not) it is unlikely that there was blinding.