Niromanesh 2005*.

Methods	Randomisation method not discussed in paper. Mirza Khochak khan Hospital, Tehran, Iran. No information on study duration.
Participants	100 women in Tehran, Iran, with fetal deaths between 14 and 25 weeks.
Interventions	Vaginal misoprostol: 400 mcg (n = 50) vs 600 mcg (n = 50) ‐ both 12‐hourly for 48 hours.
Outcomes	Miscarriage; surgical evacuation; adverse effects.
Funding	No information on funding.
Declarations of interest	No information on conflicts of interest.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Comment: randomisation method not discussed in paper.
Allocation concealment (selection bias)	Unclear risk	Comment: no information on allocation concealment.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Comment: no information on loss to follow up, number of eligible patients, etcetera.
Selective reporting (reporting bias)	Unclear risk	Comment: side effects mentioned in the results (table 2) were not mentioned in the methods section; unclear if these were all outcomes that were measured.
Other bias	Low risk	No other source of bias could be detected
Blinding of participants and personnel (performance bias) All outcomes	High risk	Comment: no information on blinding, also no statements on use of placebo. Probaby no blinding (since the difference between 2 or 3 tablets would be clear for both patients as well as personnel.
Blinding of outcome assessment (detection bias) All outcomes	High risk	Comment: no information on blinding of outcome assessment, probably not done.