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. 2019 May 29;116(24):11972–11977. doi: 10.1073/pnas.1901987116

Fig. 3.

Fig. 3.

Effects of different PFTBA nanoparticles on mice platelets. (A and B) Blood clot retraction test. Clot weight and serum weight at 90 min after mixing with different PFTBA nanoparticles or vehicle (albumin, 1.3 mg/mL; n = 3). (C and D) Representative fluorescent images and quantification of platelet adhesion treated with different PFTBA nanoparticles, platelets were prelabeled with CFSE as green (n = 4). (Scale bar: 20 μm.) (E and F) Representative fluorescent image and quantification of platelet aggregation treated with different PFTBA nanoparticles; platelets were prelabeled with CFSE as green (n = 4). (Scale bar: 100 μm.) (G) Released platelet granule contents from thrombin-activated platelets (n = 3). (H and I) Released platelet granule contents from activated platelets in vivo (n = 5).