Table 1. HDAC inhibitors in the SCAD inhibitor kits, their target HDACs, and anti-proliferative effect against Sora cells (%).
Drug name | Target HDACs | Cell survival (%) |
---|---|---|
Vorinostat | HDAC 1, 2, 3, 6 | 6.5 |
Trichostatin A | HDAC 1, 2, 3, 4, 6, 10 | 6.2 |
Scriptaid | HDAC 1, 3, 8 | 6.2 |
PCl-34051 | HDAC 8 | 40.9 |
SIRT-1 inhibitor | SIRT-1 | 98.7 |
Tenovin-6 | SIRT-1, 2, 3 | 0 |